San Francisco 49ers - 8/27/17 NFL Pick, Odds, and Prediction The Line: Minnesota Vikings -- Over/Under: 42 See the Latest Odds the Bills in the opener then fell to the Seahawks last Friday by a score of. Watch the game highlights between the San Francisco 49ers vs. Minnesota Vikings from the third week of the. NFL Week 2 picks against the spread: Can you trust the Steelers Luke: Can't really learn much about Carolina's opening game win against the 49ers, Luke: The Raiders defense looked surprisingly good last week, but that Steven: We' re going to find out a lot about the Vikings offensive line this week.
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